Questions about tumor disease

In order to be safe and get high treatment efficacy when using Crila® and Crilin® supplement  produced by Thien Duoc company, patients should avoid alcoholic beverages such as beer, wine and liquor and should not use these products in combination with other herbal medicines. If suffering from other diseases such as cardiovascular disease, blood pressure, stomachache, etc. which need to take medicines, patients should take these medicines 3-4 hours far from Crila® and Crilin® supplement to avoid interactions. In the course of using our herbal products, patients should drink smoothies or natural fruit juices like avocado, watermelon, papaya smoothies, orange juice, kudzu and pennywort juice for better digestion. Pregnant women, nursing mothers and children can not use Crila® and Crilin® supplement because these products have not been studied on these subjects.

Crila® capsule does not affect cardiovascular activity and blood pressure. We have studied Crila®  overseas and at the department of pharmacology with the conclusion: Crila® capsule does not affect cardiovascular activity and blood pressure, and safe for users. As for sexual activity in men, through the trial results on many patients during a year, there were not any cases showing that their sexual activity was affected. To have a scientific basis, we did a research project and the scientist team involved in this project concluded that Crila® capsule does not affect sexual activity of patients.

Patients can use Crila® and Crilin® supplement for a long time because these two herbal products have been studied not to affect functions of liver, kidney and other organs of the body.

People often spread experiences to take fresh leaves and dried leaves of Crinum latifolium L., then boil and drink their decoction for the prevention and treatment of tumors, which is very dangerous because the plants have not been identified as correct Crinum latifolium L. Vietnam has many plants looking alike Crinum latifolium L. such as Crinoideae, white-flower Crinum plant, etc. with the same taste, smell, color and appearance as Crinum latifolium L. So, it is difficult to distinguish whether it is Crinum latifolium L. by naked eye but with the genetic test (DNA). It should be noted that components of white-flower Crinum plant and Crinoideae are very toxic to liver, kidney, and other body’s functions.

CRILA capsule is manufactured from alkaloid and flavonoid fractions extracted from Crinum latifolium L. var. crilae Tram & Khanh which is a novel variety of Crinum latifolium L. species in Vietnam with the appropriate solvents that is non-toxic to the human body. In addition, Crinum latifolium L. var. crilae Tram & Khanh leaves used to produce CRILA are clean pharmaceutical materials collected from plantations with stable bioactivity.

So far, there have not been any scientific studies yet to prove that Crinum latifolium can cause infertility, so we can not answer this question. But Crinum latifolium L. var. crilae Tram & Khanh used as herbal materials for the production of Crila® does not affect reproductive ability or cause infertility. In fact, Crila® has been circulated for use in domestic and foreign markets since 2005. Patients with uterine fibroids have used Crila® for the treatment. After using Crila®, patients who are unable to have children could give birth to healthy and intellegent babies. This demonstrates that Crila® is safe for women of reproductive age and does not affect the impregnation. Therefore, the rumors that Crinum latifolium can cause infertility are completely inaccurate and especially Crinum latifolium L. var. crilae Tram & Khanh which is used as herbal materials for producing Crila® capsule does not cause infertility.

The studies by Doctor - Pharmacist. Nguyen Thi Ngoc Tram on Crinum latifolium L. var. crilae Tram & Khanh demonstrated the differences in gene (DNA) and chemical composition, leading to the differences in biological effects as well as the treatment efficacy. So, if you use the wrong medicinal plants or other crinum plants which have no bioactive substances inhibiting the growth of tumor cells and stimulating the immune system, they will not be effective to the treatment of benign prostatic hyperplasia (BPH) and uterine fibroids. Moreover, some crinum plants have toxicity affecting liver and kidney. There are also differences in morphological characteristics between Crinum latifolium L. var. crilae Tram & Khanh and other crinum plants, but the differences are often difficult to be recognized, but only when flowering. Crinum latifolium L. var. crilae Tram & Khanh only has flowers when it has been grown from 3 - 6 years. So, apart from experienced botanists, patients can not recognize the differences. To ensure their health, patients should choose the products from the manufacturer who has the scientific research work to provide safety and high treatment efficacy for patients.

Currently, Crila® 250mg, equivalent to 1.25mg alkaloids and Crila Forte® 500mg equivalent to 2.5mg alkaloids are allowed for circulation with indication for the treatment of benign prostatic hyperplasia (BPH) and uterine fibroids. For Crila® 250mg, the dosage is 8 capsules, 2 times daily for BPH, and 10 capsules, 2 times daily for uterine fibroids. To reduce the number of capsules taken daily from 8 to 4, Thien Duoc Co., Ltd has innovated technology and completed extraction process to create Crila Forte®. On the international market, pharmaceutical companies also produce Ampicillin with two types: Ampicillin 250mg and Ampicillin 500mg. Patients take 4 Ampicillin 250mg capsules daily, but only 2 Ampicillin 500mg capsules daily. Therefore, it’s as normal as advanced companies that Thien Duoc company manufactures Crila Forte® 500mg with a dosage of 4 capsules daily. However, to avoid confusion, patients should read the instructions carefully before use.

Crila® and Crila Forte® have the same treatment efficacy on benign prostatic hyperplasia (BPH) and uterine fibroids and difference only in the number of capsules taken daily. If you want to use Crila Forte® to treat BPH, you can take 4 capsules, 2 times daily, 15-30 minutes after meals, 3 hours after other medicines and usual time is 8 weeks. Previously you took Crila® with the dosage of 8 capsules, 2 times daily. So, Crila Forte® is more convenient for patients than Crila® because its daily dosage is half less than of Crila®’s.

If BPH and uterine fibroids are treated successfully with Crila®, patients need to continue taking Crilin® supplement with the dosage of 4 capsules, 2 times daily for 60 consecutive days to prevent tumor recurrence. After one year, repeat taking Crila® for two consecutive months.